A SYSTEMATIC COMPUTATIONAL ANALYSIS OF BIOSYNTHETIC GENE CLUSTER EVOLUTION: LESSONS FOR ENGINEERING BIOSYNTHESIS.

A systematic computational analysis of biosynthetic gene cluster evolution: lessons for engineering biosynthesis.

Bacterial secondary metabolites are widely used as antibiotics, anticancer drugs, insecticides and food additives.Attempts to engineer their biosynthetic gene clusters (BGCs) to produce unnatural metabolites with improved properties Buzz Cup are often frustrated by the unpredictability and complexity of the enzymes that synthesize these molecules,

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3D printed N-doped CoCrFeNi high entropy alloy with more than doubled corrosion resistance in dilute sulphuric acid

Abstract The traditional approaches for improving corrosion resistance of alloys typically lead to the sacrifice of mechanical properties because the microstructures needed for improving corrosion resistance often contradict those for high strength.Here we demonstrate that selected Wood Bowl laser melting (SLM), a net-shape additive manufacture tec

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